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OCTOBER 6, 2022
The Curious Case Of Accelerated Aging With HIV
By Landon Gray
The phenomenon of accelerated aging in people living with HIV is the complex result of various biological, environmental and social factors; however, it is predominantly the body’s response to the chronic inflammation associated with HIV.
“I would say the most prominent or specific reason [for accelerated aging] is a chronic inflammation that can occur,” Monica Gandhi, MD, MPH, an infectious disease and HIV specialist at the University of California, San Francisco, and the medical director of the Ward 86 HIV Clinic, in San Francisco, told Infectious Disease Special Edition.
Based on previous studies that documented the effects of HIV on aging, Dr. Gandhi explained how her clinic justified a cutoff age of 50 years for people with HIV instead of a more traditional medical milestone age of 60 or 65 in people without HIV. (See ArtClass on page 73 for more on this.)
“We have given a lot of thought to this age cutoff of 50. What I mean by that is there are some studies that look at people who are 50 living with HIV, and if you consider their endovascular system, the kind of thickening [and aging] of their vessels, they look more like they’re 60,” Dr. Gandhi said.
Continue reading... https://www.idse.net/HIV-AIDS-STIs/Article/10-22/The-Curious-Case-Of-Accelerated-Aging-With-HIV/68233
"Reproduced with permission - Infectious Disease Special Edition (IDSE)"
Infectious Disease Special Edition (IDSE)
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