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www.idse.net

JULY 15, 2024

Anal Cancer Risk Differs by Region for People With HIV

By Leslie Cantu

A recent study that followed a cohort of more than 110,000 people found significant disparities in the risk for anal cancer for people with HIV and for men who have sex with men (MSM) with HIV, depending on the region of the country where they live.

It's known that people with HIV have the highest risk for anal cancer, said lead author Ashish A. Deshmukh, PhD, a co-leader of the cancer control research program at Medical University of South Carolina Hollings Cancer Center, in Charleston.

But this study shows vast geographic disparities in anal cancer risk and an association with opportunistic illnesses and comorbidities, like diabetes, chronic kidney disease and cardiovascular disease, for people with HIV (J Nation Cancer Inst 2024 May 7. https://doi.org/10.1093/jnci/djae096).

Almost all cases of anal cancer are caused by HPV. It seems that there’s some as-yet-unknown effect, such as inflammation, in people with comorbidities that allows HPV to gain a foothold and cause cancer to develop, the paper noted.

Continue reading... https://www.idse.net/HIV-AIDS-STIs/Article/07-24/Anal-Cancer-Risk-Differs-by-Region-for-People-With-HIV/74312

"Reproduced with permission - Infectious Disease Special Edition (IDSE)"

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