News Release 19-Jan-2026
58% of patients affected by 2022 mpox outbreak report lasting physical symptoms
American College of Physicians
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Below please find summaries of new articles that will be published in the next issue of Annals of Internal Medicine. The summaries are not intended to substitute for the full articles as a source of information. This information is under strict embargo and by taking it into possession, media representatives are committing to theterms of the embargo not only on their own behalf, but also on behalf of the organization they represent.
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1. 58% of patients affected by 2022 mpox outbreak report lasting physical symptoms
Abstract: https://www.acpjournals.org/doi/10.7326/ANNALS-25-00036
Summary for Patients: https://www.acpjournals.org/doi/10.7326/ANNALS-25-00036-PS
A cohort study of over 300 adults either diagnosed with mpox between May 2022 to January 2023 (post-MPX) and or who were at risk but never infected (no-MPX) found that more than half of those diagnosed with mpox during the 2022 outbreak still had lingering physical effects 11 to 18 months later. Most reported appearance-related changes, and some continued to experience anorectal or urinary problems. The study is published in Annals of Internal Medicine.
Researchers from the Centers for Disease Control and Prevention, Columbia University Division of Infectious Diseases, and University of Texas Health Science Center Houston sought to understand the long-term psychosocial and behavioral impact between at-risk persons who had or did not have mpox during the 2022 mpox outbreak. The researchers recruited post-MPX and no-MPX participants from health centers in New York City, NY and Houston, TX to complete psychosocial and behavioral self-assessments followed by a clinical evaluation among the post-MPX group. The study found that 58% of those infected had at least one persistent symptom. Among post-MPX participants with appearance-related sequelae, the extent of sequelae was relatively low, with most having fewer than 10 scars or sites of discoloration and 2 or fewer body sites involved. Thirteen percent of post-MPX participants experienced ongoing physical function changes, and 2% had their activities of daily living affected. The findings provide context into the enduring physical and psychosocial effects that may occur because of mpox.
Media contacts: For an embargoed PDF, please contact Gabby Macrina at gmacrina@acponline.org. To contact corresponding author Preetam Cholli, MD, please submit a CDC Request for Comment Form.
Media Contact
Gabby Macrina
American College of Physicians
gmacrina@acponline.org
Office: 215-351-2513
Source: https://www.eurekalert.org/news-releases/1112498
"Reproduced with permission - American College of Physicians"
American College of Physicians
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